Endocrine Abstracts

Introduction: The term female pattern hair loss (FPHL) is commonly used synonymously with female androgenetic alopecia. While the the role of androgens and androgen receptor genes is well-defined in male androgenetic alopecia (AGA-M), its role in in the pathogenesis of FPHL is stil uncertain. More diffuse involvement, resulting in an oval-shaped alopecia surrounded by a rim of normal hair density (Luduig’s classification) might be a clinical challenge. The aim of case rep...

Background: In the 2019 ESC Guidelines on diabetes, pre-diabetes and cardiovascular diseases, only retinopathy appears as a target organ damage as a parameter for stratification patients into very high-risk group. The aim of study was to check the strength of association between DN and isolated DR groups with cardiovascular complications.Methods: Chronic kidney disease (CKD) was defined by eGFR ≤ 59 ml/min/1.73 m2 and proteinuria (P...

Introduction: The fact that up to 33% with type 2 diabetes develop hypogonadotropic hypogonadisms (HH), are still not catching enough attention. More futher ’’the 5-year mortality of somebody who has got diabetes, who has had a myocardial infarction is actually lower than the diabetic patient who has developed a diabetic foot ulcer, which is around 48%’’.Case description: We describe male patient, 47 y. (on 2016y), newly diagnosed...

IntroductionInfertility associated with hypergonadotropism is usually an unpromising condition related to acheiving fertilization. We describe the patient presented as oligoasthenoteratozoospermia (OAT syndrome), with laboratory primary hypergonadotropic hypogonadism but normal male fenotype, including typical male hair dustribution.Case descriptionmale, born 41 year ago, presented when he was 29 year old, as...

Background and aims: In many developing countries, diabetic foot is considered as a problem only when the patient develops a wound on the foot. Until that moment, the detection of changes in the neurovascular condition of the feet is rarely applied. The aim of this prospective, single centre study was to define factors associated with early cardiovascular mortality in diabetes.Materials and methods: 1345 patients under age 75 were included who were under...

Background and aims: After two decades of silence in classification system od type 2 diabetes there are some indices that the dibebtic retinopathy might be the sign for introduction of insulin therapy. The aim of this study was to examine associations between measures of diabetic foot in people with diabetes complicated by nonproliferative retinopathy (NPDR), maculopathy and proliferative retinopathy (PDR).Materials and methods: People were included had ...

Background and aims: Foot lesions (amputations, ulcerations) are the consequence of neuro-vascular complications. Cardiovascular risk factors are similar for both. Thus, we carried out a prospective 5-year study to examine the effects of established complications and classical risk factors on mortality in diabetic patients.Materials and methods: During the previous 5 years we analyzed 244 patients attending a diabetes clinic. The International Working Gr...

Introduction: Biological casuses of levothyroxine (LT4) malabsorption are well known. Congestive heart failure, gastrointestinal diseases, pregnancy, medication or dietary interference are the most commonly known causes of poor oral absorption of LT4. However, when substitution therapy with LT4 fails we need to be more exploratory.Case description: Female, born in 1987, BH 164 cm, BW 73kg, in 2010 she was presented as M. Basedowi and in october 2011 near...

Introduction: Acute hepatic porphyria is a relatively rare metabolic disorder. Its typical clinical manifeastations are abdominal symptoms and/or troubles belonging to the cerebral oedema. Clinical picture of acute abdomen is frequent and unsuccessful surgical treatment leads to the diagnosis of porphyria.Case description: Female, born in 1987, presented in emergency surgical unit as appendictis. She was operated but the problems did not disappear. After...